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filingDate 2020-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f730902582962f7ee1027511f9b6cc4f
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publicationDate 2020-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2020117531-A
titleOfInvention New synthetic method of catechin
abstract PROBLEM TO BE SOLVED: To provide a novel method for synthesizing enantiomerically pure form or enantiomerically enriched form and/or racemic form of epicatechin. A process for the synthesis of enantiomerically pure or enantiomerically enriched (+ and/or -) epicatechin and its intermediates or a racemic mixture of (+ and/or) epicatechin and its intermediates Therefore, the following steps: (i) a step of obtaining the penta-protected quercetin; (ii) a step of reducing the penta-protected quercetin obtained from the step (i); (iii) a deprotection of the compound of the step (ii) if necessary. Step; (iv) Step of reducing the compound obtained from Step (ii) or Step (iii) in the presence of a chiral/achiral reducing agent to obtain a chiral intermediate; (v) Obtained from Step (iv) Deprotecting and/or hydrogenating a chiral intermediate to give (-)-epicatechin; (vi) optionally deprotecting and hydrogenating the compound obtained from step (ii) to give racemic epicatechin A process that includes steps. [Selection diagram] None
priorityDate 2013-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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