| abstract |
PROBLEM TO BE SOLVED: To provide a novel natural protein which can be used for prevention and treatment of diseases caused by excessive production or accumulation of junk proteins. A secreted protein sDSS1 of higher primate can bind to an oxidized protein to form a polymer or bind to an Aβ polypeptide to reduce the formation of an Aβ oligomer in a non-enzymatic condition. it can. It can also block the cytotoxicity caused by oxidized proteins, Aβ oligomers, amylin oligomers and glycosylated proteins. The protein is used for prevention and treatment of diseases caused by the accumulation of oxidized protein, glycated protein, Aβ protein, accumulation of amylin protein, or excessive production or accumulation of other pathogenic proteins having similar properties. obtain. [Selection diagram] None |