| abstract |
PROBLEM TO BE SOLVED: To provide a novel guanidine derivative or a pharmaceutically acceptable salt thereof, which exhibits an excellent effect of suppressing cancer cell growth, cancer metastasis and cancer recurrence even at a lower dose than existing drugs, and a method for preparing the same. I will provide a. SOLUTION: N1-phenethyl N2-(4-bromo)phenyl biguanide, N1-(4-chloro)benzyl-N2-cycloheptyl biguanide, N1-(benzo[d][1,3]dioxol-5-yl) Guanidine derivatives such as methyl-N2-ethyl biguanide. Effectively used for the prevention or treatment of various cancers such as uterine cancer, breast cancer, gastric cancer, brain cancer, rectal cancer, colon cancer, lung cancer, skin cancer, blood cancer, liver cancer and the suppression of cancer cell proliferation and cancer metastasis be able to. [Selection diagram] None |