| abstract |
PROBLEM TO BE SOLVED: To provide an efficient platform useful for the design and production of novel modified multispecific antibodies and antibody-like molecules. SOLUTION: A modified J chain having an exogenous binding moiety introduced into the J chain of a native sequence having a specific amino acid sequence, an antibody containing the modified J chain or an antigen-binding fragment thereof, and a composition containing the antibody. And a method for treating a tumor or a viral disease using the antibody. [Selection diagram] None |