abstract |
PROBLEM TO BE SOLVED: To use a novel human anti-PD-1, PD-L1 and PD-L2 antibody to obtain a symptom that benefits from regulation of PD-1, PD-L1 and/or PD-L2 activity (for example, Compositions and methods for diagnosing, prognosing, and treating persistent infections, autoimmune diseases, asthma, graft rejection, inflammatory diseases and tumors. An isolated chimeric, humanized, conjugated, or human anti-PD-1, PD-L1, and a heavy chain CDR comprising a specific amino acid sequence; or a light chain CDR comprising a specific amino acid sequence. PD-L2 antibody, or an antigen-binding fragment thereof. [Selection diagram] None |