abstract |
PROBLEM TO BE SOLVED: To provide a novel cell-permeable succinate and a cell-permeable precursor of succinate for the purpose of increasing ATP production in mitochondria. A compound represented by formula (I) or a pharmaceutically acceptable salt thereof. (In the formula, the dotted bond between A and B represents an arbitrary bond forming a closed ring structure, Z is —CH 2 —CH 2 —, or >CH(CH 3 ); -SR, -OR, or NHR; B is -OR', -NHR", -SR'", or -OH; R is a specific substituent having a carboxyl group; R', R'. ", R'" is independently a specific substituent having a carboxyl group or the like.) [Selection diagram] None |