| abstract |
PROBLEM TO BE SOLVED: To provide a composition and a method for enhancing an immune response by partial mTOR inhibition using a low immunopotentiating dose of mTOR inhibitor such as RAD001. The use of a low, immunopotentiating dose of a mTOR inhibitor to promote an immune response in a subject, and thereby enhance or enhance the immune response. Use as described above, wherein the mTOR inhibitor is an allosteric mTOR inhibitor or a catalytic inhibitor, RAD001 or rapamycin. The use as described above, wherein the catalytic inhibitor is a kinase inhibitor. [Selection diagram] None |