| abstract |
PROBLEM TO BE SOLVED: To provide a method for producing 4-alkoxy-3-hydroxypicolinic acid. 4,6-Dibromo-3-hydroxypicolinonitrile may be prepared from furfural in a series of chemical steps selected from cyano-amination, amine salt formation and bromination-rearrangement. 4-Alkoxy-3-hydroxypicolinic acid is conveniently prepared from 4,6-dibromo-3-hydroxypicolinonitrile in a series of chemical steps selected from bromine substitution, nitrile hydrolysis and halogen reduction. Can be manufactured. [Selection diagram] None |