| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df493aec811c46b53ab16f0e1a115b8a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 |
| filingDate |
2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1b50f540a59a29ba07c63f650f7d25f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e780a7a47182f0b531032b4c0cc46e52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3df87d9fdf6edfc553c2ce52b60d01d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f5797ba68df8208a8a1a100c5682b2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_858743ee5283c2ce319256bfde6c40f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1302f8c47358d04c067a5c3190d6ab20 |
| publicationDate |
2020-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2020072766-A |
| titleOfInvention |
Chemically modified mRNA |
| abstract |
PROBLEM TO BE SOLVED: To provide a method and a composition for producing and optimizing a modified mRNA molecule by changing the terminal structure of the molecule. SOLUTION: The synthetic isolated end-optimized mRNA according to the present invention comprises (a) a first region of a binding nucleoside encoding a polypeptide of interest, and (b) at least one translation enhancer element (TEE). A first end region located 5 ′ to the first region containing (c) a second end region located 3 ′ to the first region, and (d) ) A 3'tail of the linked nucleoside. [Selection diagram] Figure 2 |
| priorityDate |
2012-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |