| abstract |
Emulsion systems and micromolded ("MM") or three-dimensionally printed ("3DP") polymers for single injection of antigens, preferably released over two or more periods of time To provide a formulation. The formulation is preferably formed from a biocompatible, biodegradable polymer. A separate area encapsulating the antigen is present in the formulation, alone or in combination with other antigens, adjuvants, stabilizers, and release modifiers. The antigen is preferably present in the excipient at the time of administration, or present on the surface of the formulation for immediate release, and optionally released 10-45 days after the initial release of the antigen. , Incorporated into the formulation for release of the antigen at 10-90 day intervals for one or more additional periods. [Selection diagram] None |