| abstract |
Kind Code: A1 Abstract: Compresses into tablets having sufficient hardness / friability, acceptable disintegration time, low moisture sensitivity, improved stability, acceptable dissolution pattern and improved pharmacokinetic properties in the treated patient, preferably Provide a pharmaceutical tablet formulation that can be directly compressed. The following components per unit dosage form, tablet: Formula (a): Wherein R is substituted adamantyl and n is an integer from 0 to 3, the compound as an active ingredient or a pharmaceutically acceptable salt thereof, (b) when present in a 1% solution A pharmaceutical tablet formulation comprising hydroxypropyl methylcellulose having a viscosity of 80,000 cP to 120,000 cP (nominal value 100,000 cP), (c) microcrystalline cellulose, and (d) magnesium stearate. [Selection diagram] None |