| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c52b29f85805b5683ea92a6c85e8fc6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_851a327d25463a2a5c46bc8268a21eaf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2019-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a6ea5ad776c68ebafcdd862cd8e187c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67827b61a673b533f47955addfa493b2 |
| publicationDate |
2020-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2020037599-A |
| titleOfInvention |
Manufacture and use of novel therapeutic anticancer drugs |
| abstract |
The present invention provides a composition for reprogramming the properties of malignant human cancer cells to a low-grade benign or normal somatic cell-like state. The composition comprises at least one microribonucleic acid precursor (pre-miRNA) containing the sequence of SEQ.ID.NO.3 at a concentration of 1 mg / mL or less, wherein the pre-miRNA comprises: SEQ ID NO: SEQ ID NO: used in contact with a cell subject comprising at least one human cancer cell to induce reprogramming of the human cancer cell to a low-stage benign or normal somatic cell-like state. The pre-miRNA containing the sequence of .NO.3 is produced in prokaryotic cells by using transcription of RNA driven by a eukaryotic promoter. [Selection diagram] FIG. |
| priorityDate |
2012-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |