| abstract |
The present invention provides a pharmaceutical use of a polypeptide having angiotensin converting enzyme 2 activity which can be mass-produced at low cost. SOLUTION: Hypertension, heart failure, heart tissue fibrosis, comprising a polypeptide derived from a prokaryotic microorganism having angiotensin converting enzyme 2 activity and having a specific amino acid sequence in its active site or a derivative thereof as an active ingredient, The present invention relates to a pharmaceutical composition for treating or preventing acute respiratory distress syndrome or acute lung injury. [Selection diagram] None |