abstract |
PROBLEM TO BE SOLVED: To solve the problem. aureus vaccine, in particular a plurality of S. aureus vaccines. To identify further improved antigens for vaccines useful against Aureus pathology. [Solution] Various combinations of Aureus antigens are identified for use in immunization. These polypeptides may optionally be S. Aureus sugars may be used in combination. We have the following 36 polypeptides: clfA, clfB, coA, eap, ebhA, ebpS, efb, em, esaC, esxA, esxB, FnBA, FnBB, Hla, hlgB, hlgC, isdA, isdB, isdC, isdG, isdH, isdI, lukD, lukE, lukF, lukS, nuc, sasA, sasB, sasC, sasD, sasF, sdrC, sdrD, spa, and sdrE2 were identified. [Selection diagram] None |