| abstract |
The present invention provides compounds for targeted immunotherapy and compositions containing them. The present invention has the structure of formula (I), TM-Ln-AM (I), wherein TM specifically binds to an antigen expressed on tumor cells, and directly or indirectly. In particular, a target moiety comprising an immunoglobulin or a functional fragment thereof capable of inhibiting cell proliferation or inducing apoptosis, wherein AM specifically binds to human TLR7 and TLR8 and , An activating moiety that activates dendritic cells, NK cells, or both, wherein L is a linker and n is an integer selected from 0 and 1. [Selection diagram] None |