Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2736f182a3b15933d2f933de9801289 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-60 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2869 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-531 |
filingDate |
2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e3e8735f729eac95d8f5015e4592a09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bbe6da8e28d42436ea31d0bc1559ea5 |
publicationDate |
2020-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2020005651-A |
titleOfInvention |
Methods and compositions for producing binding agents for cell surface antigens |
abstract |
【Task】 Provided are methods and compositions for identifying a binding polypeptide (eg, an antibody or antigen-binding fragment thereof) that specifically binds to a cell surface antigen. To enable the identification of novel therapeutically useful cell type-specific antigens or epitopes. [Solution] A diverse nucleic acid display library of binding polypeptides is contacted with a cell surface antigen displayed on the external surface of the cell, and at least one of the libraries that specifically binds to a cell surface antigen on the external surface of the cell A method for isolating one library member is provided. Also provided are nucleic acid display libraries (eg, DNA display libraries) that can be used to screen for novel binding polypeptides useful in the methods of the present invention. [Selection diagram] None |
priorityDate |
2013-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |