| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf522b8b83eded745c73018576219ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82cbc291d77c061ac9a216f86ec010a3 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 |
| filingDate |
2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_376781877bc7b935e3482b2ea98f378f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91a2d140b46ef1934a0121e52b0e2de7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a95a772def4fc2eabd1593f25dd1430c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd46b36e0af7cf876138d860428cbe30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72421da9b3ffb5a7246d1e4b22422799
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ff59129eb4613bd28d81b7b43fb26a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da72e634f600b57f30814323e6e95040
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6bffdd532e7efc02a9e630acde600d4 |
| publicationDate |
2020-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2020002075-A |
| titleOfInvention |
Cross-Linking Antibodies Bind to Human and Rat Renal Epithelial Podoplanin and Variable Region Fragments thereof |
| abstract |
An object of the present invention is to provide an antibody or a low-molecular antibody having a target cross-linking property capable of targeting both rat and human renal epithelial podoplanin. The present invention has at least one amino acid sequence of the following six CDRs, or has at least one amino acid sequence containing addition, substitution, or deletion of one to several amino acids in the amino acid sequence of the following six CDRs. A cross-linked antibody or cross-linked antibody variable region fragment that binds to human and rat renal epithelial podoplanin having at least one amino acid sequence having at least 80% identity to the amino acid sequences of the following six CDRs: Chain CDR1: DYGVN (SEQ ID NO: 1) heavy chain CDR2: VIWGGGNTYYNSALKS (SEQ ID NO: 2) heavy chain CDR3: HRGA (SEQ ID NO: 3) light chain CDR1: KSSQSLLNSGNQKNYLI (SEQ ID NO: 4) Light chain CDR2: WASTRES (SEQ ID NO: 5) Light chain CDR3: QNDHTYPLT (SEQ ID NO: 6). [Selection diagram] None |
| priorityDate |
2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |