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filingDate 2018-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c7725155a1aaf3a5c0e89620cd61120
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publicationDate 2020-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2020002014-A
titleOfInvention Inhibitory activity and its purification method
abstract An object of the present invention is to provide an inhibitor using a fungal strain of the genus Aspergillus (Aspergillus udagawae IFM54302), which is capable of effectively exhibiting platelet aggregation inhibitory activity and cancer cell growth inhibitory effect. It is. The inhibitory activity of the present invention is obtained by purifying a fungal strain of the genus Aspergillus (Aspergillus udagawae IFM54302), and AU-1a (1R, 2S) -specified by the absolute stereochemical structural formula of Chemical formula 1. Methyl 2,8-dihydroxy-6- (hydroxymethyl) -9-oxo-2,9-dihydro-1H-xanthene-1-carboxylate and AU-1b (absolute stereochemical structural formula) Racemic form of 1S, 2R) -methyl 2,8-dihydroxy-6- (hydroxymethyl) -9-oxo-2,9-dihydro-1H-xanthen-1-carboxylate and AU-1a and AU-1b And AU-1ab. [Selection diagram] Fig. 1
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115466241-A
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