abstract |
The present invention provides a compound of formula (I) wherein R 1 , R 2 , R 2A , R 3 , R 3A , R 4 , R 4A , and R 5 are as defined herein. ] Is disclosed. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their manufacture, pharmaceutical compositions containing them, and methods of treating cystic fibrosis by administering the compounds of the present invention. is there. |