abstract |
The present disclosure relates to condensed N-arylsulfonamidyl-thienoisoquinoline compounds, derivatives thereof, and pharmaceutical compositions, and methods and uses for suppressing cancer cell growth using supplemental anticancer agents. Centrosome targeting and microtubule depolymerization are attractive in the design of chemotherapeutic compounds of the present invention. Various diseases and conditions to be treated include various types of cell carcinoma and in vitro inhibition. [Chemical 1] [Selection figure] None |