abstract |
Methods of treating focal segmental glomerulosclerosis using a compound of formula I are provided. FSGS can be primary (cause is not known) or secondary. Secondary FSGS is overfiltered with infections or viruses such as HIV, diseases such as sickle cell disease or lupus, toxins or drugs such as anabolic steroids, heroin or pamidronate, nephron loss, and chronic pyelonephritis and reflux, May be associated with morbid obesity or diabetes. [Selection] Figure 1 |