http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019532641-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-528 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-526 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 |
filingDate | 2017-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2019532641-A |
titleOfInvention | Improved method for selecting polypeptide producing cells |
abstract | In the 5 ′ to 3 ′ direction, (i) a first nucleic acid fragment encoding a polypeptide of interest without an in-frame translation stop codon, and (ii) 5 of an immunoglobulin heavy chain CH3 or CH4 domain. 'Functional to the first nucleic acid fragment starting from the splice donor site and ending at the 3' splice acceptor site of the subsequent immunoglobulin heavy chain transmembrane domain exon M1 and containing an in-frame translation stop codon and a polyadenylation signal And (iii) a third nucleic acid fragment operably linked to the second nucleic acid encoding at least one fragment of the transmembrane 10 domain, 2 nucleic acid fragments have the nucleotide sequence CTACCACCCCCTTCCTGTCCAG (SEQ ID NO: 29) or TGACCACGCCAATCGTGTCCAG (SEQ ID NO: 14) or CTACCACGCCAATCGTGTCCAG (SEQ ID NO: 31) at their 3 ′ end, nucleic acids reported herein Is done. |
priorityDate | 2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1111.