Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-22 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70539 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
filingDate |
2017-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2019532255-A |
titleOfInvention |
Combination of reversible and irreversible cell labeling for analyzing receptor-ligand koff rates |
abstract |
The present invention relates to a method for determining the dissociation rate constant (k off ) of a receptor molecule R on a target cell using a combination of reversible and irreversible cell labeling. The invention further relates to a cell comprising such a receptor molecule R, wherein such a cell label combination is bound to the receptor molecule R. The invention further relates to kits and equipment useful for performing the methods of the invention. The present invention further relates to a method for isolating high avidity T cells. |
priorityDate |
2016-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |