| abstract |
As used herein, an effective amount of at least one active ingredient, a crystal structure-forming agent in an amount of about 5% to about 40% by weight, based on the total weight of the lyophilized dosage form, and at least one mucoadhesive agent Disclosed is a solid lyophilized vaginal dosage form that may have a polymeric matrix forming agent. The pH of the dosage form can be about 4.0-5.0 and can disintegrate within 120 seconds after contacting the vaginal mucosa. A method of delivering the active ingredient to the vaginal mucosa using the disclosed solid dosage forms is also described. |