| abstract |
The present invention relates to eye disorders, skin disorders, conditions associated with damaging effects from erosive agents, and autoimmune diseases, inflammatory diseases due to the use of toxic aldehydes such as primary amines scavenging MDA and HNE. Compounds and methods for the treatment, prevention, and / or reduction of the risk of diseases, disorders, or conditions in which aldehyde toxicity is associated with pathogenesis, including nervous system diseases and cardiovascular diseases. The compounds of the invention and compositions thereof are useful for treating, preventing and / or reducing the risk of diseases, disorders or conditions in which aldehyde toxicity is associated with pathogenesis. |