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filingDate 2016-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2019531339-A
titleOfInvention Polymyxin B sulfate crystal and method for producing the same
abstract The present invention provides polymyxin B sulfate crystals and a method for producing the same. The production method of the present invention comprises a step of adsorbing a polymyxin B fermentation solution to a resin and adding and desorbing sulfuric acid or acidic ethanol; a step of concentrating to obtain a saturated solution of polymyxin B sulfate; and an organic solvent. Using to precipitate crystals from the saturated solution, followed by filtration and drying to obtain polymyxin B sulfate crystals. [Selection] Figure 1A
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