http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019530438-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3616 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 |
| filingDate | 2017-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2019530438-A |
| titleOfInvention | Compositions and methods for programming adult cells with platelet rich fractions of blood containing platelet-like cells |
| abstract | The described invention provides a method for functionally reprogramming adult cells into immature cell types that express one or more embryonic biomarkers. Reprogramming contacts adult cells with a platelet-rich fraction, including platelet-like cells derived from umbilical cord blood or peripheral blood, and expresses human beta cell-specific transcription factors and is functional with human pancreatic beta cells Achieved by growing immature cell types in vitro under culture conditions that produce an insulin producing cell population that is equivalent to Without being limited by theory, platelet-like cells and their released mitochondria display tolerance-related markers that can regulate immune cell function and differentiation. The described invention further comprises a pharmaceutical composition comprising a cell product containing a therapeutic amount of an insulin producing cell population derived from functionally reprogrammed adult cells, wherein the insulin producing cell population is human beta cell specific A pharmaceutical composition is provided that expresses a transcription factor and is functionally equivalent to human pancreatic beta cells. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023079655-A1 |
| priorityDate | 2016-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 283.