| abstract |
The present disclosure relates to multivalent pneumococcal vaccine compositions comprising pneumococcal capsular polysaccharide serotypes, each individually conjugated to a carrier protein. In the conjugated state, the combination of pneumococcal capsular polysaccharide serotype and carrier is referred to herein as a polysaccharide-protein conjugate. The pneumococcal vaccine composition can further comprise one or more of the following: a pharmaceutically acceptable carrier, pharmaceutically acceptable diluent, buffer, preservative, stabilizer, adjuvant, and / or lyophilized. Excipients. Also provided are methods of making and administering the pneumococcal vaccine compositions described herein. [Selection] Figure 1 |