| abstract |
The present disclosure features novel lipids and compositions containing the same. Lipid nanoparticles include novel lipids as well as additional lipids such as phospholipids, structured lipids, and PEG lipids. A therapeutic and / or prophylactic agent, eg, a lipid nanoparticle further comprising RNA, delivers the therapeutic and / or prophylactic agent to a mammalian cell or organ, eg, to modulate polypeptide, protein, or gene expression Useful in. |