| abstract |
Herein, a recombinant fusion polypeptide comprising an antibody heavy chain variable domain, a multimerization domain, and an antibody light chain variable domain is reported, wherein the antibody heavy chain variable domain is one of the multimerization domains. Fusing to the end (either directly or via a first (peptide) linker), the antibody light chain domain is either directly or second (directly or to the other end of the multimerization domain). The peptide (either via a linker) is fused, and the antibody heavy chain variable domain or antibody light chain domain has a (intrapeptide) disulfide bond to the multimerization domain. |