abstract |
The present invention relates to antibody drug conjugates using bispecific antibodies and uses thereof. The antibody-drug conjugate of the present invention easily forms a complex between an antibody and a drug without a multi-step synthesis process by binding a bivalent cotinin-peptide and drug conjugate to an anti-cotinine single-chain variable section. can do. In addition, the antibody-drug conjugate of the present invention can effectively deliver the drug to the target to which the antibody specifically binds, and can increase the half-life of the in-vivo drug and improve the therapeutic effect. |