| abstract |
An anti-PD-1 monoclonal antibody or antigen-binding fragment thereof is provided. (1) amino acid sequence shown in SEQ ID NO: 1, (2) amino acid sequence shown in SEQ ID NO: 3, (3) amino acid sequence shown in SEQ ID NO: 5, (4) in comparison with (1) to (3) It comprises a heavy chain variable region having at least one amino acid sequence selected from an amino acid sequence having at least one conservative amino acid mutation. 【Selection chart】 None |