| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-191
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-177
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70575 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
| filingDate |
2017-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2019-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2019517570-A |
| titleOfInvention |
Methods of selecting and treating patients using TRAIL-based therapeutic agents or cell death receptor agonists |
| abstract |
Provided herein are methods for identifying cancer patients (eg, colorectal cancer) who would benefit from treatment with TRAIL-based therapeutics or cell death receptor agonists based on their levels of DR4 and cIAP1. Also provided are methods of treating a patient diagnosed with cancer (eg, colorectal cancer) based on its levels of DR4 and cIAP1. Also provided is a method of treating a cancer patient determined to have a particular level of one or more biomarkers (DR4 and / or cIAP1) by administration of a TRAIL-based therapeutic or death receptor agonist. 【Selection chart】 None |
| priorityDate |
2016-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |