abstract |
The present invention relates to chemistry, medicine, and, in particular, phenolic compounds in combination with tricyclics of the type having benzodiazepine fused to derivatives of 1,4-dihydropyridine, which have an effect on the central nervous system and the vasculature The present invention relates to the preparation of formulations from derivatives of polyphenolic compounds and from derivatives of phenolic compounds or polyphenolic compounds. These pharmaceutical compositions have the effect of modulating calcium channels and exhibiting actions that are GABAergic, anti-glutamic acid, mitochondrial protective, antioxidant, anti-inflammatory and anti-apoptotic and are cardiovascular, cerebrovascular, It can be used in the treatment of neurodegenerative, neuropsychiatric and neurological disorders. |