http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019516383-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2017-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2019516383-A |
| titleOfInvention | Method of predicting the prognosis of a patient having a malignant disease and predicting responsiveness to immunotherapy |
| abstract | The present invention relates, inter alia, to a method of predicting the prognosis of a patient having a malignancy and / or a method of predicting responsiveness to immunotherapy of a patient having a malignancy. SOLUTION: For this purpose, DNA-methylation analysis is carried out on at least one immunoregulatory gene of malignant cells and / or T-lymphocyte cells which interact with malignant cells. , B7-proteins and their receptors, co-receptors that bind to MHC: peptide complexes, members of the tumor necrosis factor receptor superfamily TNFRSF9, CD40, TNFRSF4, TNFRSF18 and CD27, members of the immunoglobulin superfamily TIGIT, BTLA , HAVCR2, BTNL2 and CD48, and an immune checkpoint protein selected from the group comprising adenosine 2A receptors to which adenosine binds. [Selected figure] Figure 9 |
| priorityDate | 2016-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 776.