http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019515053-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5383 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
| filingDate | 2017-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2019515053-A |
| titleOfInvention | 2,2-Dimethyl-6-((4-((3,4,5-trimethoxyphenyl) amino) -1,3,5-triazin-2-yl) amino) -2H pyrido for medical use Novel crystalline salt form of 3,2-B] [1,4] oxazin-3 (4H) -one |
| abstract | The present invention relates to the chemistry, pharmacology and medicine of organic compounds, and to 2,2-dimethyl-6-((4-((3,4,5-trimethoxyphenyl) amino) -1,3,5 Metabolism of bone and / or cartilage tissue using a novel salt form of -triazin-2-yl) amino) -2H-pyrido [3,2-B] [1,4] oxazin-3 (4H) -one The present invention relates to the prevention and treatment of human and animal diseases associated with disorders, in particular musculoskeletal diseases such as osteoarthritis or osteoporosis. Salts (I) of this compound with 4-methylbenzenesulfonic acid (including hydrates and solvates thereof, and homomorphs of the salts, hydrates and solvates thereof) of kinases of the Src family , Syk kinase, and other therapeutically important kinases, as well as enhanced efficacy of inhibition, as well as acceptable pharmacokinetic parameters. The invention also relates to a pharmaceutical composition comprising a therapeutically effective amount of a salt according to the invention. |
| priorityDate | 2016-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 281.