Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-01011 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-01011 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate |
2017-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2019514395-A |
titleOfInvention |
Penicillin G acylase |
abstract |
The present invention provides engineered penicillin G acylase (PGA) enzymes with improved properties, polynucleotides encoding such enzymes, compositions comprising those enzymes, and methods of using those enzymes . The present invention uses phenylacetate monoprotected or diprotected with phenylacetate by adding a protecting group to the A1, B1 or B29 position of free insulin or removing the protecting group from the A1 / B1 / B29 triprotected insulin Provided is an engineered penicillin G acylase that can be produced. |
priorityDate |
2016-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |