| abstract |
The present disclosure relates to substituted heterocyclic derivative therapeutic compounds, compositions comprising the above compounds, and above compounds for epigenetics control by inhibition of bromo domain mediated recognition of acetyl lysine regions of proteins such as histones. And use of the composition. The compositions and methods are useful for the treatment of diseases mediated by abnormal signal transduction such as inflammatory disorders, cancer and neoplastic diseases. 【Selection chart】 None |