http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019513726-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
filingDate | 2017-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2019513726-A |
titleOfInvention | Anti-complement Bb factor antibody and use thereof |
abstract | The present disclosure provides an anti-complement factor Bb antibody, and a composition comprising the antibody. Anti-Bb antibodies are useful for treating complement-mediated disorders. The present disclosure provides methods of treating complement mediated disorders. In some cases, the antibody binds to human complement Bb protein with an affinity of at least 10 -8 M. In some cases, the antibody inhibits C3b / Bb mediated cleavage of C3. In some cases, the antibody comprises a humanized light chain framework region. In some cases, the antibody comprises a humanized heavy chain framework region. In some cases, the antibody comprises a humanized light chain framework region and a humanized heavy chain framework region. [Selected figure] Figure 1 |
priorityDate | 2016-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1223.