| abstract |
The present invention relates to a soluble micro-nidle, wherein the skin is pierced with the micro-noodle and then the micro-noodle is dissolved when the micro-noodle is inserted through the pierced skin. The present invention relates to a micro-nidol wherein a target substance in the nido is administered into the skin and a micro-nidol patch comprising the micro-nidol. By using the micro-noodle according to the present invention, it can be easily inserted into the skin without morphological changes such as flexion or breakage, because it has appropriate mechanical strength, viscosity and hardness, and effective skin perforation is possible. It becomes. In addition, since the micro nido according to the present invention is dissolved through the perforated skin while showing the excellent skin permeability of the target substance, it is not necessary to apply a strong force, and any part of the micro nido is aimed at Substances can also be effectively delivered into the skin. |