abstract |
Provided herein are methods, kits, and compositions for identifying a subject at risk of developing acute kidney injury. These methods, kits, and compositions are useful in identifying subjects at risk of developing acute kidney injury prior to undergoing surgical intervention such as cardiovascular surgery or initiating chemotherapy. is there. In particular, p16 and / or p14 levels are useful to identify the risk of acute kidney injury in these subjects. Also described herein are non-naturally occurring DNA sequences corresponding to some or all of p16 and / or p14, which are useful in identifying subjects at risk of developing acute kidney injury. [Selected figure] Figure 1 |