http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019508457-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
| filingDate | 2017-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2019508457-A |
| titleOfInvention | Combination therapy for proliferative diseases |
| abstract | 【Task】 A compound of the following formula (I) or a salt thereof, and a compound of the following formula (X) or a tautomer or pharmaceutically acceptable salt thereof or a hydrate or solvate thereof Combined product. R-L-CO-X (I) Wherein R is a C 10-24 unsaturated hydrocarbon group optionally interrupted by one or more heteroatoms or heteroatomic groups selected from S, O, N, SO, SO 2 , said carbonized Hydrogen groups contain at least 4 non-conjugated double bonds; L is a linking group which forms a bridge of 1 to 5 atoms between the R group and the carbonyl CO, wherein L comprises at least one heteroatom in the backbone of said linking group; X is an electron withdrawing group; [Chemical formula 1] In which R 1 is phenyl, said phenyl being substituted with unsubstituted lower alkyl or lower alkyl substituted with cyano; R 3 is lower alkyl such as methyl; and R 4 is unsubstituted quinolinyl or quinolinyl substituted with halogen. 【Selection chart】 None |
| priorityDate | 2016-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.