abstract |
The present disclosure relates to compositions and methods for treating inflammatory conditions including, but not limited to, ocular inflammation, dry eye disease, and ocular neuropathic pain, among others. One aspect of the present disclosure relates to a composition comprising (a) a chemerin or fragment or analog thereof, and (b) a lipid entity linked to the chemerin or fragment or analog thereof. The lipid entity may be linked to chemerin or a fragment or analog thereof via a linker comprising polyethylene glycol, a peptide, or a combination thereof. |