abstract |
The present invention relates to the pathogenesis of cryptosporidiosis and / or the administration of a therapeutic agent that antagonizes or modulates the activity of phosphatidylinositol-4-OH kinase (PI4K), which is a lipid kinase of cryptosporidium protozoa. Or relates to methods for treating, preventing, inhibiting, ameliorating, or eradicating a general condition. In one embodiment, the therapeutic agent is a pyrazolo [1,5-a] pyridine compound of Formula (I), or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein the variable is As defined herein. |