| abstract |
Described herein are carboxamide derivatives useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in the treatment of diseases or disorders associated with RSK activity. ,be written. Such carboxamide derivatives form bicyclic and tricyclic ring systems, and the disease or condition associated with RSK activity in mammals is cancer. [Selection] Figure 16B |