| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6093 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5153
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2017-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2019-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2019504895-A |
| titleOfInvention |
TIMP encapsulating cedar pollen epitope (tissue metalloprotease inhibitor) |
| abstract |
[PROBLEMS] To develop cedar pollinosis in a subject suffering from cedar pollinosis, considering the considerable prevalence of this disease, particularly in Japan and neighboring countries, and the possibility of antibody cross-reactivity between coniferous pollen. There is a need in the art for safe and effective means to induce tolerance to cedar pollen antigens (eg, CRYJ1 and CRYJ2) in subjects at risk. The present invention provides a composition comprising particles having a negative zeta potential that encapsulates one or more epitopes associated with cedar pollen. Also provided is a method of inducing immunological tolerance to cedar pollen by administering the particles. [Selection] Figure 1 |
| priorityDate |
2016-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |