abstract |
A device for determining an analyte concentration (eg, glucose) is disclosed. The device comprises a sensor configured to generate a signal related to the concentration of the analyte and a sensing membrane located on the sensor. The sensing membrane includes an enzyme layer that includes an enzyme and a polymer that includes polyurethane and / or polyurea segments and one or more zwitterionic repeat units. The enzyme layer protects the enzyme and prevents it from leaching or inactivating from the sensing membrane to the host. |