abstract |
The present invention relates to a compound of formula (I), (2S) -3-([1,1′-biphenyl] -4-ylsulfonyl) -N-[(1S) -3-hydroxy-1-phenylpropyl] -1, L-valinate esters of hydroxypropylthiazolidinecarboxamide derivatives of 3-thiazolidine-2-carboxamide, and salts and crystal polymorphs thereof are provided. The compounds inhibit the prostaglandin F receptor (PGF2alpha) and are useful in the treatment of disorders such as premature labor or dysmenorrhea in early pregnancy. |