| abstract |
The present disclosure is directed to antibody-drug conjugates. More particularly, the present disclosure provides (i) an antibody-drug conjugate comprising benzodiazepine and (ii) a composition containing a small hydrophobic molecule, a therapeutic method using the composition, and formulating the composition. Is directed to the method. Furthermore, the present disclosure is directed to methods for reducing reversible self-association in antibodies and in antibody-drug conjugates. [Selection] Figure 1 |