| abstract |
A method for promoting and inhibiting proliferation of hematopoietic stem cells in a subject, comprising administering a hematopoietic stem cell modulator and a pharmaceutically acceptable carrier. The substance promoting proliferation of hematopoietic stem cells is prostaglandin (PG) E2, PGI2, linoleic acid, mead acid, eicosatrienoic acid, epoxy eicosatrienoic acid, forskolin, fendiline, nicardipine, nifedipine, Pimozide, strophantidine, lanatoside, L-arginine, sodium nitroprusside, sodium vanadate, bradykinin, atenolol, pindolol, hydralazine, and the like, and substances that inhibit the growth of hematopoietic stem cells include indomethacin, fenbufen, sulindac, suxibzone , Aspirin, naproxen, ibuprofen, celecoxib, PGJ2, aristolochic acid, and the like, for promoting and inhibiting proliferation of hematopoietic stem cells. [Selection figure] None |